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Lichen sclerosus (LS) is a chronic inflammatory skin condition causing itching, pain, and skin thinning. While corticosteroids are the standard treatment, cannabinoids like CBD and CBG show promise in reducing inflammation, calming nerve-related itching, and supporting skin repair. Though clinical studies on LS are lacking, research suggests CBD’s anti-inflammatory and soothing effects may help. CBD-infused lubricants may also improve moisture, reduce pain, and enhance comfort during intimacy. With a strong safety profile, combining a CBD tincture for systemic relief and a topical for targeted support is a low-risk, high-reward option—because hydrated, less irritated skin is always a win.